Diabetes mellitus (DM) occurs when the pancreas does not produce sufficient insulin, or when the body cannot effectively use the insulin. Hyperglycaemia causes a disturbance in carbohydrate, protein, and fat metabolism along with long-term damage to vital tissues such as the retina, kidney, and nervous system via non-enzymatic protein glycosylation. The major goal in treating diabetes is to minimise blood glucose elevation.
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Effects on Islet Regeneration and Glucokinase Activity
